BDBM50259973 CHEMBL4098403
SMILES C[C@]1(CCSC(N)=N1)c1cc(CNC2(CC2)C(F)(F)F)c(F)cc1F
InChI Key InChIKey=XKONRMXLBXCJAM-AWEZNQCLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50259973
Affinity DataIC50: 18nMAssay Description:Inhibition of BACE1 in human H4 cells expressing wild type APP695 assessed as reduction in soluble APPbeta level after 18 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of BACE1 (unknown origin) using biotin-GLTNIKTEEISEISYEVEFR-C[oregon green]KK-OH as substrate after 3 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair